Paired involvement of human-specific Olduvai domains and NOTCH2NL genes in human brain evolution

Sequences encoding Olduvai (DUF1220) protein domains show the largest human-specific increase in copy number of any coding region in the genome and have been linked to human brain evolution. Most human-specific copies of Olduvai (119/165) are encoded by three NBPF genes that are adjacent to three hu...

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Detalles Bibliográficos
Autores principales: Fiddes, Ian T., Pollen, Alex A., Davis, Jonathan M., Sikela, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611739/
https://www.ncbi.nlm.nih.gov/pubmed/31087184
http://dx.doi.org/10.1007/s00439-019-02018-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611739/
https://www.ncbi.nlm.nih.gov/pubmed/31087184
http://dx.doi.org/10.1007/s00439-019-02018-4

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