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Paired involvement of human-specific Olduvai domains and NOTCH2NL genes in human brain evolution
Sequences encoding Olduvai (DUF1220) protein domains show the largest human-specific increase in copy number of any coding region in the genome and have been linked to human brain evolution. Most human-specific copies of Olduvai (119/165) are encoded by three NBPF genes that are adjacent to three hu...
Autores principales: | Fiddes, Ian T., Pollen, Alex A., Davis, Jonathan M., Sikela, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611739/ https://www.ncbi.nlm.nih.gov/pubmed/31087184 http://dx.doi.org/10.1007/s00439-019-02018-4 |
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