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A novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization

The Pannexin 1 (Panx1) ion and metabolite channel is expressed in a wide variety of cells where it regulates a number of cell behaviours including proliferation and differentiation. Panx1 is expressed on the cell surface as well as intracellular membranes. Previous work suggests that a region within...

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Detalles Bibliográficos
Autores principales: Epp, Anna L., Ebert, Sarah N., Sanchez-Arias, Juan C., Wicki-Stordeur, Leigh E., Boyce, Andrew K. J., Swayne, Leigh Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611761/
https://www.ncbi.nlm.nih.gov/pubmed/31278290
http://dx.doi.org/10.1038/s41598-019-46144-5