Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling

Upper tract urothelial carcinoma (UTUC) is characterized by a distinctly aggressive clinical phenotype. To define the biological features driving this phenotype, we performed an integrated analysis of whole-exome and RNA sequencing of UTUC. Here we report several key insights from our molecular diss...

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Detalles Bibliográficos
Autores principales: Robinson, Brian D., Vlachostergios, Panagiotis J., Bhinder, Bhavneet, Liu, Weisi, Li, Kailyn, Moss, Tyler J., Bareja, Rohan, Park, Kyung, Tavassoli, Peyman, Cyrta, Joanna, Tagawa, Scott T., Nanus, David M., Beltran, Himisha, Molina, Ana M., Khani, Francesca, Miguel Mosquera, Juan, Xylinas, Evanguelos, Shariat, Shahrokh F., Scherr, Douglas S., Rubin, Mark A., Lerner, Seth P., Matin, Surena F., Elemento, Olivier, Faltas, Bishoy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611775/
https://www.ncbi.nlm.nih.gov/pubmed/31278255
http://dx.doi.org/10.1038/s41467-019-10873-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611775/
https://www.ncbi.nlm.nih.gov/pubmed/31278255
http://dx.doi.org/10.1038/s41467-019-10873-y

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