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Uncovering biomarker genes with enriched classification potential from Hallmark gene sets

Given the complex relationship between gene expression and phenotypic outcomes, computationally efficient approaches are needed to sift through large high-dimensional datasets in order to identify biologically relevant biomarkers. In this report, we describe a method of identifying the most salient...

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Detalles Bibliográficos
Autores principales: Targonski, Colin A., Shearer, Courtney A., Shealy, Benjamin T., Smith, Melissa C., Feltus, F. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611793/
https://www.ncbi.nlm.nih.gov/pubmed/31278367
http://dx.doi.org/10.1038/s41598-019-46059-1