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Iron overload reduces synthesis and elimination of bile acids in rat liver

Excessive iron accumulation in the liver, which accompanies certain genetic or metabolic diseases, impairs bile acids (BA) synthesis, but the influence of iron on the complex process of BA homeostasis is unknown. Thus, we evaluated the effect of iron overload (IO) on BA turnover in rats. Compared wi...

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Detalles Bibliográficos
Autores principales: Prasnicka, Alena, Lastuvkova, Hana, Alaei Faradonbeh, Fatemeh, Cermanova, Jolana, Hroch, Milos, Mokry, Jaroslav, Dolezelova, Eva, Pavek, Petr, Zizalova, Katerina, Vitek, Libor, Nachtigal, Petr, Micuda, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611795/
https://www.ncbi.nlm.nih.gov/pubmed/31278332
http://dx.doi.org/10.1038/s41598-019-46150-7