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Iron overload reduces synthesis and elimination of bile acids in rat liver
Excessive iron accumulation in the liver, which accompanies certain genetic or metabolic diseases, impairs bile acids (BA) synthesis, but the influence of iron on the complex process of BA homeostasis is unknown. Thus, we evaluated the effect of iron overload (IO) on BA turnover in rats. Compared wi...
Autores principales: | Prasnicka, Alena, Lastuvkova, Hana, Alaei Faradonbeh, Fatemeh, Cermanova, Jolana, Hroch, Milos, Mokry, Jaroslav, Dolezelova, Eva, Pavek, Petr, Zizalova, Katerina, Vitek, Libor, Nachtigal, Petr, Micuda, Stanislav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611795/ https://www.ncbi.nlm.nih.gov/pubmed/31278332 http://dx.doi.org/10.1038/s41598-019-46150-7 |
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