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Retinal myeloid cells regulate tip cell selection and vascular branching morphogenesis via Notch ligand Delta-like 1

During angiogenesis, single endothelial cells (EC) specialize into tip cells that guide vessel sprouting towards growth factor gradients and instruct the adjacent vessel stalk. The balance between tip and stalk cells is regulated by endothelial Notch signalling through the expression of Notch ligand...

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Detalles Bibliográficos
Autores principales: Haupt, Fabian, Krishnasamy, Kashyap, Napp, L. Christian, Augustynik, Michael, Limbourg, Anne, Gamrekelashvili, Jaba, Bauersachs, Johann, Haller, Hermann, Limbourg, Florian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611798/
https://www.ncbi.nlm.nih.gov/pubmed/31278348
http://dx.doi.org/10.1038/s41598-019-46308-3