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Actin stabilizing compounds show specific biological effects due to their binding mode

Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a structurally related prototypic actin stabilizer. Though both compounds have similar effects on cytoskeletal morphology and proliferation, they aff...

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Detalles Bibliográficos
Autores principales: Wang, Shuaijun, Crevenna, Alvaro H., Ugur, Ilke, Marion, Antoine, Antes, Iris, Kazmaier, Uli, Hoyer, Maria, Lamb, Don C., Gegenfurtner, Florian, Kliesmete, Zane, Ziegenhain, Christoph, Enard, Wolfgang, Vollmar, Angelika, Zahler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611809/
https://www.ncbi.nlm.nih.gov/pubmed/31278311
http://dx.doi.org/10.1038/s41598-019-46282-w