Pax 6 Controls Neural Crest Potential of Limbal Niche Cells to Support Self-Renewal of Limbal Epithelial Stem Cells

On ocular surface, corneal epithelial stem cells (SC) reside in limbus between cornea and conjunctiva. Pax6, an evolutionally conserved transcription factor essential for eye development, is expressed in post-natal corneal and limbal epithelia progenitors (LEPC) but not in underlying stroma. Because...

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Detalles Bibliográficos
Autores principales: Chen, Szu-Yu, Cheng, Anny M. S., Zhang, Yuan, Zhu, Ying-Ting, He, Hua, Mahabole, Megha, Tseng, Scheffer C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611810/
https://www.ncbi.nlm.nih.gov/pubmed/31278274
http://dx.doi.org/10.1038/s41598-019-45100-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611810/
https://www.ncbi.nlm.nih.gov/pubmed/31278274
http://dx.doi.org/10.1038/s41598-019-45100-7

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