Delayed recruiting of TPD52 to lipid droplets – evidence for a “second wave” of lipid droplet-associated proteins that respond to altered lipid storage induced by Brefeldin A treatment

Tumor protein D52 (TPD52) is amplified and overexpressed in breast and prostate cancers which are frequently characterised by dysregulated lipid storage and metabolism. TPD52 expression increases lipid storage in mouse 3T3 fibroblasts, and co-distributes with the Golgi marker GM130 and lipid droplet...

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Detalles Bibliográficos
Autores principales: Chen, Yuyan, Frost, Sarah, Khushi, Matloob, Cantrill, Laurence C., Yu, Hong, Arthur, Jonathan W., Bright, Robert K., Groblewski, Guy E., Byrne, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611826/
https://www.ncbi.nlm.nih.gov/pubmed/31278300
http://dx.doi.org/10.1038/s41598-019-46156-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611826/
https://www.ncbi.nlm.nih.gov/pubmed/31278300
http://dx.doi.org/10.1038/s41598-019-46156-1

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