Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which the intricate alveolar network of the lung is progressively replaced by fibrotic scars. Myofibroblasts are the effector cells that excessively deposit extracellular matrix proteins thus compromising lung structure and function. Emerging...

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Detalles Bibliográficos
Autores principales: Kheirollahi, Vahid, Wasnick, Roxana M., Biasin, Valentina, Vazquez-Armendariz, Ana Ivonne, Chu, Xuran, Moiseenko, Alena, Weiss, Astrid, Wilhelm, Jochen, Zhang, Jin-San, Kwapiszewska, Grazyna, Herold, Susanne, Schermuly, Ralph T., Mari, Bernard, Li, Xiaokun, Seeger, Werner, Günther, Andreas, Bellusci, Saverio, El Agha, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611870/
https://www.ncbi.nlm.nih.gov/pubmed/31278260
http://dx.doi.org/10.1038/s41467-019-10839-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611870/
https://www.ncbi.nlm.nih.gov/pubmed/31278260
http://dx.doi.org/10.1038/s41467-019-10839-0

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