The Bivalent Rewarding and Aversive properties of Δ(9)-tetrahydrocannabinol are Mediated Through Dissociable Opioid Receptor Substrates and Neuronal Modulation Mechanisms in Distinct Striatal Sub-Regions

The primary psychoactive compound in cannabis, Δ(9)-tetrahydrocannabinol (THC), is capable of producing bivalent rewarding and aversive affective states through interactions with the mesolimbic system. However, the precise mechanisms underlying the dissociable effects of THC are not currently unders...

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Detalles Bibliográficos
Autores principales: Norris, Christopher, Szkudlarek, Hanna J., Pereira, Brian, Rushlow, Walter, Laviolette, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611878/
https://www.ncbi.nlm.nih.gov/pubmed/31278333
http://dx.doi.org/10.1038/s41598-019-46215-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611878/
https://www.ncbi.nlm.nih.gov/pubmed/31278333
http://dx.doi.org/10.1038/s41598-019-46215-7

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