Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation

Mesangial cell (MC) proliferation is one of the important pathological features of obesity-associated nephropathy with unknown etiology. Excessive MC proliferation can cause glomerulosclerosis and renal function loss. Thus, targeting MC proliferation may be a potential strategy for the treatment of...

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Detalles Bibliográficos
Autores principales: Sun, Zhenzhen, Li, Yuanyuan, Qian, Yun, Wu, Mengying, Huang, Songming, Zhang, Aihua, Zhang, Yue, Jia, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611885/
https://www.ncbi.nlm.nih.gov/pubmed/31285857
http://dx.doi.org/10.1038/s41420-019-0196-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611885/
https://www.ncbi.nlm.nih.gov/pubmed/31285857
http://dx.doi.org/10.1038/s41420-019-0196-0

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