Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7

In the central nervous system (CNS), oligodendrocytes myelinate multiple axons; in the peripheral nervous system (PNS), Schwann cells (SCs) myelinate a single axon. Why are the myelinating potentials of these glia so fundamentally different? Here, we find that loss of Fbxw7, an E3 ubiquitin ligase c...

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Detalles Bibliográficos
Autores principales: Harty, Breanne L., Coelho, Fernanda, Pease-Raissi, Sarah E., Mogha, Amit, Ackerman, Sarah D., Herbert, Amy L., Gereau, Robert W., Golden, Judith P., Lyons, David A., Chan, Jonah R., Monk, Kelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611888/
https://www.ncbi.nlm.nih.gov/pubmed/31278268
http://dx.doi.org/10.1038/s41467-019-10881-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611888/
https://www.ncbi.nlm.nih.gov/pubmed/31278268
http://dx.doi.org/10.1038/s41467-019-10881-y

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