Lysosome Inhibition by Mefloquine Preferentially Enhances the Cytotoxic Effects of Tyrosine Kinase Inhibitors in Blast Phase Chronic Myeloid Leukemia()

Despite the efficacy of BCR-ABL tyrosine kinase inhibitors (TKIs) in chronic phase-chronic myeloid leukemia, the management of blast phase-chronic myeloid leukemia (BP-CML) remains a challenge. Therefore, there is an urgent need to identify alternative agents that act synergistically with BCR-ABL TK...

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Detalles Bibliográficos
Autores principales: Lam Yi, Hui, Than, Hein, Sng, Colin, Cheong, May Anne, Chuah, Charles, Xiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611990/
https://www.ncbi.nlm.nih.gov/pubmed/31276961
http://dx.doi.org/10.1016/j.tranon.2019.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611990/
https://www.ncbi.nlm.nih.gov/pubmed/31276961
http://dx.doi.org/10.1016/j.tranon.2019.06.001

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