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Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX)-induced tissue injury, we previously found that...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612011/ https://www.ncbi.nlm.nih.gov/pubmed/31276937 http://dx.doi.org/10.1016/j.redox.2019.101237 |