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IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells

BACKGROUND: Natural killer (NK) cells are an emerging new tool for cancer immunotherapy. To develop NK cell therapeutics from peripheral blood mononuclear cells (PBMCs) of healthy donors, substantial expansion of primary NK cells is necessary because of the very low number of these cells in peripher...

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Detalles Bibliográficos
Autores principales: Choi, Yeon Ho, Lim, Eun Jin, Kim, Se Wha, Moon, Yong Wha, Park, Kyung Soon, An, Hee-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612093/
https://www.ncbi.nlm.nih.gov/pubmed/31277710
http://dx.doi.org/10.1186/s40425-019-0652-7