Targeting mTOR for cancer therapy

Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival, metabolism, and immunity. mTOR is usually assembled into several complexes such as mTOR complex 1/2 (mTORC1/2). In cooperation with raptor, rictor, LST8, and mSin1, key components in mTORC1 or mTORC2, mTOR c...

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Detalles Bibliográficos
Autores principales: Hua, Hui, Kong, Qingbin, Zhang, Hongying, Wang, Jiao, Luo, Ting, Jiang, Yangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612215/
https://www.ncbi.nlm.nih.gov/pubmed/31277692
http://dx.doi.org/10.1186/s13045-019-0754-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612215/
https://www.ncbi.nlm.nih.gov/pubmed/31277692
http://dx.doi.org/10.1186/s13045-019-0754-1

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