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MicroRNA-181c Suppresses the Biological Progression of Osteosarcoma via Targeting SMAD7 and Regulating Transforming Growth Factor-β (TGF-β) Signaling Pathway

BACKGROUND: Osteosarcoma is a primary bone aggressive cancer, affecting adolescents worldwide. Increasing evidence suggests that dysfunction of microRNAs (miRNAs) plays a pivotal role in malignancies. The aim of this study was to evaluate the potential functions of miR-181c and verifying its regulat...

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Detalles Bibliográficos
Autores principales: Fu, Youwei, Tang, Yin, Wang, Junjie, Guo, Zonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612243/
https://www.ncbi.nlm.nih.gov/pubmed/31251735
http://dx.doi.org/10.12659/MSM.916939