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Evidence to date: talazoparib in the treatment of breast cancer

Approximately 5–10% of all patients diagnosed with breast cancer have germline BRCA1/2 mutations, which make their disease more susceptible to DNA-damaging agents and a new class of drugs known as poly(ADP-ribose) polymerase (PARP) inhibitors. Talazoparib is a new PARP inhibitor that has been recent...

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Detalles Bibliográficos
Autores principales: Exman, Pedro, Barroso-Sousa, Romualdo, Tolaney, Sara M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612288/
https://www.ncbi.nlm.nih.gov/pubmed/31303769
http://dx.doi.org/10.2147/OTT.S184971