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Evidence to date: talazoparib in the treatment of breast cancer
Approximately 5–10% of all patients diagnosed with breast cancer have germline BRCA1/2 mutations, which make their disease more susceptible to DNA-damaging agents and a new class of drugs known as poly(ADP-ribose) polymerase (PARP) inhibitors. Talazoparib is a new PARP inhibitor that has been recent...
Autores principales: | Exman, Pedro, Barroso-Sousa, Romualdo, Tolaney, Sara M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612288/ https://www.ncbi.nlm.nih.gov/pubmed/31303769 http://dx.doi.org/10.2147/OTT.S184971 |
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