Restored immune cell functions upon clearance of senescence in the irradiated splenic environment

Some studies show eliminating senescent cells rejuvenate aged mice and attenuate deleterious effects of chemotherapy. Nevertheless, it remains unclear whether senescence affects immune cell function. We provide evidence that exposure of mice to ionizing radiation (IR) promotes the senescent‐associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Palacio, Lina, Goyer, Marie‐Lyn, Maggiorani, Damien, Espinosa, Andrea, Villeneuve, Norbert, Bourbonnais, Sara, Moquin‐Beaudry, Gaël, Le, Oanh, Demaria, Marco, Davalos, Albert R., Decaluwe, Hélène, Beauséjour, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612633/
https://www.ncbi.nlm.nih.gov/pubmed/31148373
http://dx.doi.org/10.1111/acel.12971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612633/
https://www.ncbi.nlm.nih.gov/pubmed/31148373
http://dx.doi.org/10.1111/acel.12971

Ejemplares similares