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Restored immune cell functions upon clearance of senescence in the irradiated splenic environment
Some studies show eliminating senescent cells rejuvenate aged mice and attenuate deleterious effects of chemotherapy. Nevertheless, it remains unclear whether senescence affects immune cell function. We provide evidence that exposure of mice to ionizing radiation (IR) promotes the senescent‐associat...
Autores principales: | Palacio, Lina, Goyer, Marie‐Lyn, Maggiorani, Damien, Espinosa, Andrea, Villeneuve, Norbert, Bourbonnais, Sara, Moquin‐Beaudry, Gaël, Le, Oanh, Demaria, Marco, Davalos, Albert R., Decaluwe, Hélène, Beauséjour, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612633/ https://www.ncbi.nlm.nih.gov/pubmed/31148373 http://dx.doi.org/10.1111/acel.12971 |
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