Alignment-free filtering for cfNA fusion fragments

MOTIVATION: Cell-free nucleic acid (cfNA) sequencing data require improvements to existing fusion detection methods along multiple axes: high depth of sequencing, low allele fractions, short fragment lengths and specialized barcodes, such as unique molecular identifiers. RESULTS: AF4 was developed t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiao, Saito, Yasushi, Rao, Arjun, Kim, Hyunsung John, Singh, Pranav, Scott, Eric, Larson, Matthew, Pan, Wenying, Desai, Mohini, Hubbell, Earl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Ismb/Eccb 2019 Conference Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612805/
https://www.ncbi.nlm.nih.gov/pubmed/31510681
http://dx.doi.org/10.1093/bioinformatics/btz346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612805/
https://www.ncbi.nlm.nih.gov/pubmed/31510681
http://dx.doi.org/10.1093/bioinformatics/btz346

Ejemplares similares