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Statistical compression of protein sequences and inference of marginal probability landscapes over competing alignments using finite state models and Dirichlet priors

The information criterion of minimum message length (MML) provides a powerful statistical framework for inductive reasoning from observed data. We apply MML to the problem of protein sequence comparison using finite state models with Dirichlet distributions. The resulting framework allows us to supe...

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Detalles Bibliográficos
Autores principales: Sumanaweera, Dinithi, Allison, Lloyd, Konagurthu, Arun S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612809/
https://www.ncbi.nlm.nih.gov/pubmed/31510703
http://dx.doi.org/10.1093/bioinformatics/btz368