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Using the structure of genome data in the design of deep neural networks for predicting amyotrophic lateral sclerosis from genotype
MOTIVATION: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by aberrations in the genome. While several disease-causing variants have been identified, a major part of heritability remains unexplained. ALS is believed to have a complex genetic basis where non-additive combin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612814/ https://www.ncbi.nlm.nih.gov/pubmed/31510706 http://dx.doi.org/10.1093/bioinformatics/btz369 |