In silico error correction improves cfDNA mutation calling

MOTIVATION: Circulating-free DNA (cfDNA) profiling by sequencing is an important minimally invasive protocol for monitoring the mutation profile of solid tumours in cancer patients. Since the concentration of available cfDNA is limited, sample library generation relies on multiple rounds of PCR ampl...

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Detalles Bibliográficos
Autores principales: Kim, Chang Sik, Mohan, Sumitra, Ayub, Mahmood, Rothwell, Dominic G, Dive, Caroline, Brady, Ged, Miller, Crispin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612818/
https://www.ncbi.nlm.nih.gov/pubmed/30520956
http://dx.doi.org/10.1093/bioinformatics/bty1004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612818/
https://www.ncbi.nlm.nih.gov/pubmed/30520956
http://dx.doi.org/10.1093/bioinformatics/bty1004

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