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PRISM: methylation pattern-based, reference-free inference of subclonal makeup
MOTIVATION: Characterizing cancer subclones is crucial for the ultimate conquest of cancer. Thus, a number of bioinformatic tools have been developed to infer heterogeneous tumor populations based on genomic signatures such as mutations and copy number variations. Despite accumulating evidence for t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612819/ https://www.ncbi.nlm.nih.gov/pubmed/31510697 http://dx.doi.org/10.1093/bioinformatics/btz327 |