Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology

MOTIVATION: The composition and density of immune cells in the tumor microenvironment (TME) profoundly influence tumor progression and success of anti-cancer therapies. Flow cytometry, immunohistochemistry staining or single-cell sequencing are often unavailable such that we rely on computational me...

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Detalles Bibliográficos
Autores principales: Sturm, Gregor, Finotello, Francesca, Petitprez, Florent, Zhang, Jitao David, Baumbach, Jan, Fridman, Wolf H, List, Markus, Aneichyk, Tatsiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Ismb/Eccb 2019 Conference Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612828/
https://www.ncbi.nlm.nih.gov/pubmed/31510660
http://dx.doi.org/10.1093/bioinformatics/btz363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612828/
https://www.ncbi.nlm.nih.gov/pubmed/31510660
http://dx.doi.org/10.1093/bioinformatics/btz363

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