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Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology
MOTIVATION: The composition and density of immune cells in the tumor microenvironment (TME) profoundly influence tumor progression and success of anti-cancer therapies. Flow cytometry, immunohistochemistry staining or single-cell sequencing are often unavailable such that we rely on computational me...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612828/ https://www.ncbi.nlm.nih.gov/pubmed/31510660 http://dx.doi.org/10.1093/bioinformatics/btz363 |