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hicGAN infers super resolution Hi-C data with generative adversarial networks

MOTIVATION: Hi-C is a genome-wide technology for investigating 3D chromatin conformation by measuring physical contacts between pairs of genomic regions. The resolution of Hi-C data directly impacts the effectiveness and accuracy of downstream analysis such as identifying topologically associating d...

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Detalles Bibliográficos
Autores principales: Liu, Qiao, Lv, Hairong, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612845/
https://www.ncbi.nlm.nih.gov/pubmed/31510693
http://dx.doi.org/10.1093/bioinformatics/btz317