Integrating read-based and population-based phasing for dense and accurate haplotyping of individual genomes

MOTIVATION: Reconstruction of haplotypes for human genomes is an important problem in medical and population genetics. Hi-C sequencing generates read pairs with long-range haplotype information that can be computationally assembled to generate chromosome-spanning haplotypes. However, the haplotypes...

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Detalles Bibliográficos
Autor principal: Bansal, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Ismb/Eccb 2019 Conference Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612846/
https://www.ncbi.nlm.nih.gov/pubmed/31510646
http://dx.doi.org/10.1093/bioinformatics/btz329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612846/
https://www.ncbi.nlm.nih.gov/pubmed/31510646
http://dx.doi.org/10.1093/bioinformatics/btz329

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