Cargando…
Integrating read-based and population-based phasing for dense and accurate haplotyping of individual genomes
MOTIVATION: Reconstruction of haplotypes for human genomes is an important problem in medical and population genetics. Hi-C sequencing generates read pairs with long-range haplotype information that can be computationally assembled to generate chromosome-spanning haplotypes. However, the haplotypes...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612846/ https://www.ncbi.nlm.nih.gov/pubmed/31510646 http://dx.doi.org/10.1093/bioinformatics/btz329 |