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Large-scale mammalian genome rearrangements coincide with chromatin interactions

MOTIVATION: Genome rearrangements drastically change gene order along great stretches of a chromosome. There has been initial evidence that these apparently non-local events in the 1D sense may have breakpoints that are close in the 3D sense. We harness the power of the Double Cut and Join model of...

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Detalles Bibliográficos
Autores principales: Swenson, Krister M, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612848/
https://www.ncbi.nlm.nih.gov/pubmed/31510664
http://dx.doi.org/10.1093/bioinformatics/btz343