Inferring signalling dynamics by integrating interventional with observational data

MOTIVATION: In order to infer a cell signalling network, we generally need interventional data from perturbation experiments. If the perturbation experiments are time-resolved, then signal progression through the network can be inferred. However, such designs are infeasible for large signalling netw...

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Detalles Bibliográficos
Autores principales: Cardner, Mathias, Meyer-Schaller, Nathalie, Christofori, Gerhard, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Ismb/Eccb 2019 Conference Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612850/
https://www.ncbi.nlm.nih.gov/pubmed/31510686
http://dx.doi.org/10.1093/bioinformatics/btz325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612850/
https://www.ncbi.nlm.nih.gov/pubmed/31510686
http://dx.doi.org/10.1093/bioinformatics/btz325

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