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Inferring signalling dynamics by integrating interventional with observational data
MOTIVATION: In order to infer a cell signalling network, we generally need interventional data from perturbation experiments. If the perturbation experiments are time-resolved, then signal progression through the network can be inferred. However, such designs are infeasible for large signalling netw...
Autores principales: | Cardner, Mathias, Meyer-Schaller, Nathalie, Christofori, Gerhard, Beerenwinkel, Niko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612850/ https://www.ncbi.nlm.nih.gov/pubmed/31510686 http://dx.doi.org/10.1093/bioinformatics/btz325 |
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