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Drug repositioning based on bounded nuclear norm regularization

MOTIVATION: Computational drug repositioning is a cost-effective strategy to identify novel indications for existing drugs. Drug repositioning is often modeled as a recommendation system problem. Taking advantage of the known drug–disease associations, the objective of the recommendation system is t...

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Detalles Bibliográficos
Autores principales: Yang, Mengyun, Luo, Huimin, Li, Yaohang, Wang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612853/
https://www.ncbi.nlm.nih.gov/pubmed/31510658
http://dx.doi.org/10.1093/bioinformatics/btz331