Inference of clonal selection in cancer populations using single-cell sequencing data

SUMMARY: Intra-tumor heterogeneity is one of the major factors influencing cancer progression and treatment outcome. However, evolutionary dynamics of cancer clone populations remain poorly understood. Quantification of clonal selection and inference of fitness landscapes of tumors is a key step to...

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Detalles Bibliográficos
Autores principales: Skums, Pavel, Tsyvina, Viachaslau, Zelikovsky, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Ismb/Eccb 2019 Conference Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612866/
https://www.ncbi.nlm.nih.gov/pubmed/31510696
http://dx.doi.org/10.1093/bioinformatics/btz392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612866/
https://www.ncbi.nlm.nih.gov/pubmed/31510696
http://dx.doi.org/10.1093/bioinformatics/btz392

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