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Selfish: discovery of differential chromatin interactions via a self-similarity measure
MOTIVATION: High-throughput conformation capture experiments, such as Hi-C provide genome-wide maps of chromatin interactions, enabling life scientists to investigate the role of the three-dimensional structure of genomes in gene regulation and other essential cellular functions. A fundamental probl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612869/ https://www.ncbi.nlm.nih.gov/pubmed/31510653 http://dx.doi.org/10.1093/bioinformatics/btz362 |