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A statistical simulator scDesign for rational scRNA-seq experimental design
MOTIVATION: Single-cell RNA sequencing (scRNA-seq) has revolutionized biological sciences by revealing genome-wide gene expression levels within individual cells. However, a critical challenge faced by researchers is how to optimize the choices of sequencing platforms, sequencing depths and cell num...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612870/ https://www.ncbi.nlm.nih.gov/pubmed/31510652 http://dx.doi.org/10.1093/bioinformatics/btz321 |