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A statistical simulator scDesign for rational scRNA-seq experimental design

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) has revolutionized biological sciences by revealing genome-wide gene expression levels within individual cells. However, a critical challenge faced by researchers is how to optimize the choices of sequencing platforms, sequencing depths and cell num...

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Detalles Bibliográficos
Autores principales: Li, Wei Vivian, Li, Jingyi Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612870/
https://www.ncbi.nlm.nih.gov/pubmed/31510652
http://dx.doi.org/10.1093/bioinformatics/btz321