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Collaborative intra-tumor heterogeneity detection

MOTIVATION: Despite the remarkable advances in sequencing and computational techniques, noise in the data and complexity of the underlying biological mechanisms render deconvolution of the phylogenetic relationships between cancer mutations difficult. Besides that, the majority of the existing datas...

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Detalles Bibliográficos
Autores principales: Khakabimamaghani, Sahand, Malikic, Salem, Tang, Jeffrey, Ding, Dujian, Morin, Ryan, Chindelevitch, Leonid, Ester, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612880/
https://www.ncbi.nlm.nih.gov/pubmed/31510674
http://dx.doi.org/10.1093/bioinformatics/btz355