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Bayesian metabolic flux analysis reveals intracellular flux couplings

MOTIVATION: Metabolic flux balance analysis (FBA) is a standard tool in analyzing metabolic reaction rates compatible with measurements, steady-state and the metabolic reaction network stoichiometry. Flux analysis methods commonly place model assumptions on fluxes due to the convenience of formulati...

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Detalles Bibliográficos
Autores principales: Heinonen, Markus, Osmala, Maria, Mannerström, Henrik, Wallenius, Janne, Kaski, Samuel, Rousu, Juho, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612884/
https://www.ncbi.nlm.nih.gov/pubmed/31510676
http://dx.doi.org/10.1093/bioinformatics/btz315