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Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

The TNF blockade therapy is currently a well-established treatment option for a variety of autoimmune diseases such as rheumatoid arthritis (RA), psoriasis or Crohn's disease, given the proinflammatory role of TNF in the course of these diseases. Importantly, TNF neutralization is also used for...

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Detalles Bibliográficos
Autores principales: Alvarez, Maite, Otano, Itziar, Minute, Luna, Ochoa, Maria Carmen, Perez-Ruiz, Elisabeth, Melero, Ignacio, Berraondo, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612890/
https://www.ncbi.nlm.nih.gov/pubmed/31309173
http://dx.doi.org/10.15698/cst2019.07.193