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Polo-like kinase 1 inhibition in NSCLC: mechanism of action and emerging predictive biomarkers

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Due to often unspecific disease symptoms, locally advanced or metastatic disease is diagnosed in the majority of all cases. Palliative treatment options comprise of conventional cytotoxic agents, immunotherapy with ch...

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Detalles Bibliográficos
Autores principales: Stratmann, Jan A, Sebastian, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612950/
https://www.ncbi.nlm.nih.gov/pubmed/31308774
http://dx.doi.org/10.2147/LCTT.S177618