Novel peptide myristoly-CM4 induces selective cytotoxicity in leukemia K562/MDR and Jurkat cells by necrosis and/or apoptosis pathway

Purpose: There is an urgent need for the development of novel, effective, and less toxic drugs to treat leukemia. Antimicrobial peptides (AMPs) have received much more attention as alternative chemotherapeutic agents. This study aimed to examined the cytotoxicity of a novel AMP myristoly-CM4 against...

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Detalles Bibliográficos
Autores principales: Zhang, Huidan, Han, Dongju, Lv, Tongtong, Liu, Kehang, Yang, Yunqing, Xu, Xixi, Chen, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612960/
https://www.ncbi.nlm.nih.gov/pubmed/31308628
http://dx.doi.org/10.2147/DDDT.S207224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612960/
https://www.ncbi.nlm.nih.gov/pubmed/31308628
http://dx.doi.org/10.2147/DDDT.S207224

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