Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacy

In mammals, the master circadian clock synchronizes daily rhythms of physiology and behavior with the day–night cycle. Failure of synchrony, which increases the risk for numerous chronic diseases, can be treated by phase adjustment of the circadian clock pharmacologically, for example, with melatoni...

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Detalles Bibliográficos
Autores principales: Kim, Dae Wook, Chang, Cheng, Chen, Xian, Doran, Angela C, Gaudreault, Francois, Wager, Travis, DeMarco, George J, Kim, Jae Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613017/
https://www.ncbi.nlm.nih.gov/pubmed/31353796
http://dx.doi.org/10.15252/msb.20198838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613017/
https://www.ncbi.nlm.nih.gov/pubmed/31353796
http://dx.doi.org/10.15252/msb.20198838

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