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How the avidity of polymerase binding to the –35/–10 promoter sites affects gene expression

Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters, hampering our ability to characterize the myriad sequenced regulatory architectures as well as to design new synthetic...

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Detalles Bibliográficos
Autores principales: Einav, Tal, Phillips, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613100/
https://www.ncbi.nlm.nih.gov/pubmed/31196959
http://dx.doi.org/10.1073/pnas.1905615116