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A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex

B lymphocytes have the ability to sense thousands of structurally different antigens and produce cognate antibodies against these molecules. For this they carry on their surface multiple copies of the B cell antigen receptor (BCR) comprising the membrane-bound Ig (mIg) molecule and the Igα/Igβ heter...

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Detalles Bibliográficos
Autores principales: Gottwick, Cornelia, He, Xiaocui, Hofmann, Andreas, Vesper, Niklas, Reth, Michael, Yang, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613136/
https://www.ncbi.nlm.nih.gov/pubmed/31209055
http://dx.doi.org/10.1073/pnas.1907481116