The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells

The linear ubiquitin assembly complex (LUBAC) comprises 3 components: HOIP, HOIL-1, and Sharpin, of which HOIP and HOIL-1 are both members of the RBR subfamily of E3 ubiquitin ligases. HOIP catalyses the formation of Met1-linked ubiquitin oligomers (also called linear ubiquitin), but the function of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelsall, Ian R., Zhang, Jiazhen, Knebel, Axel, Arthur, J. Simon C., Cohen, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613137/
https://www.ncbi.nlm.nih.gov/pubmed/31209050
http://dx.doi.org/10.1073/pnas.1905873116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613137/
https://www.ncbi.nlm.nih.gov/pubmed/31209050
http://dx.doi.org/10.1073/pnas.1905873116

Ejemplares similares